what do you need to do?
If you need better chat capabilities than iChat provides, go download Adium.
http://www.adiumx.com/
Make Safari better by having it not autoload every flash animation and being able to do some advanced filtering of sites:
http://hetima.com/safari/stand-e.html
Get QuikSilver for application launching from your keyboard... I personally set it to use apple-shift-up as my key combo.. it's very useful:
http://quicksilver.blacktree.com/
And if you absolutely must have pc apps or have access to a pc, go download parallels, it's pretty amazing:
http://www.parallels.com
Other than those and the macromedia apps you named I can't think of anything else.