since zango is an installed application, its using like DDE, etc to pick up the URL from the web browser active window....
so couldn't you just pass the URL you want to send the surfer to a php script that sets up frames?
coding at the top of my head:
link on affiliate website:
<a href=FrameMe.php?url=http://www.somesponsorprogram.com/afflink/id=123>click here to get some porn</a>
then FrameMe.php
<frameset rows=1,* border=0>
<frame src=junk.html name=top>
<frame src=<? print $_REQUEST["url"]; ?> name=bottom>
</frameset>
the URL in the location bar will still show the affiliate website but the content will be the intended target.... but then those programs that bust out of frames, will just cause zango to pick up the URL
Fight the brainstorming!