http://www.awok.org/worst-mistake/
Basic thesis: Agriculture was probably humanity's greatest mistake. It produced overdependence on a monolithic diet that produced serious health consequences. It produces the classic scourge of class inequality and led to gender inequality.
Interesting article but I don't buy all of it. It's refreshing to see a well-argued contrarian view though. It was written by Jared Diamond, the scholar behind the AWESOME BOOK
Guns Germs and Steel