I have a 38 that a friend of mine rigged up with a holder to my bed. Since my bedroom is a loft and I have a small house, even a really really crappy aim will hit its mark

There's also a 22 rifle in there right now so if the 6 bullets don't stop them, I have back up!
Thankfully I still have 2 pugs who can still hear and will alert me to someone/something coming into the door. Getting into my room any other way would be physically impossible (plus even *I* would hear that since it would involve ladders and rock climbing equipment).