You didn't really specify what type of organization you're trying to get a handle on. Organizing projects, organizing a schedule, organizing ideas, organizing to do lists, organizing contact info, etc etc....unfortunately, there isn't a one size fits all.
Only thing that's ever come 99% close (for my use) is a microsoft program called onenote.
I live in this thing.
onenote video demo
The full advantage of onenote is when you use it on a tabletpc (ie: pen computing)...which i do about 70% my work on..
Just depends what your organizing goals are.