I had this problem when we built my new box and put windows vista ultimate on it. It just wouldn't find the DVD drive no matter what I did. Eventually I grabbed an old drive I had laying around and that one worked fine. I went to the store and bought a new DVD drive and it worked fine. The one vista couldn't see got put in a box with xp on it and it works perfectly.
I wonder if you might be having the same issue. I think there are just some DVD drives out there that vista doesn't like.
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