I have... a growing part of my business is mainstream business. I have also tested a ton of mainstream products, programs, from ppc to mail..
It's easier to make money in porn, its easier to make it from multiple sources, its easier to build traffic, it's easier to explore and not get raped, it's all around easier in adult.
It's easier to promote your program/products in adult, to adult affiliates than it is to mainstream affiliates. It's easier to get those affiliates to try new sites and products.
The difference is when you find something that makes money in mainstream, it has a bigger chance of making a lot more money - at the affiliate level for sure.
Anyone wanting to go mainstream I would truly start with yourself. Brand 'you', your name.. be super friendly/helpful, well before you try to sell, build a following around 'you' and when it comes time to sell them, it will be way easier to move them around, do giveaways, and give you social/viral bumps when asked.
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