Nubiles Tube Script
I know it's a free script, but if they had a paid version, I'd definitely use it. Very intuitive to use, great spider tool that auto-grabs and converts clips from sponsor FHG into flv using ffmpeg. Hall of fame style rotation - everything you need to run a TGP like tube.
However, if you want to run a more advanced tube with user accounts and stuff, you should go with either Smart Tube Pro or MechBunny's script if you want customized stuff.