10-14-2010, 10:54 AM
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The People's Post
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Join Date: Dec 2008
Location: invisible 7-11
Posts: 64,588
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more infos i just read on the hypothalamus gland & obesity
Quote:
an "organic" form of obesity is seen in patients who suffer damage to an area at the base of the brain called the hypothalamus. This area, the size of a fingernail, whose primary function is to release hormones which control the function of the pituitary gland immediately below it, also controls energy balance. Damage to this area has long been known to promote excessive eating (hyperphagia) and weight gain, termed "hypothalamic obesity." This form of weight gain is not responsive to diet and exercise. Victims of this form of obesity continue to gain weight despite their best efforts, and suffer greatly from this unrelenting scourge.
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the ventromedial hypothalamus (VMH) integrates (brain) and peripheral (pancreas) signals to control energy balance. VMH damage from tumors, surgery, or radiation leads to insulin overproduction, probably mediated through the vagus nerve. Children with hypothalamic obesity overproduce insulin, a process that results in sustained and sometimes unrelenting weight gain. Some obese adults (without brain tumors) also overproduce insulin" as a result of increased activity of the vagus nerve.
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