It's a Greasemonkey script, but if you're running Google Chrome, just click install and install as if it was a typical Chrome extension.
Add someone to your vB ignore list and they're gone for good. All posts and threads...GONE.
I tested it using Paul Markham and it's functioning perfectly.
If you're looking to ignore people...this should do the trick.
http://userscripts.org/scripts/show/26567