If you notice any kind of rash stop immediately, as the rashes can become serious. Do not take if you're a bit depressive as it can make you suicidal.
"Provigil can also cause psychiatric symptoms, including anxiety, mania, hallucinations and suicidal ideation. The company advises caution when the drug is given to patients with a history of psychosis, depression or mania. If psychiatric symptoms develop, consider discontinuing the drug. "