Twelve years after giving up full-time acting to focus on fighting Parkinson's disease, Michael J Fox will star in a new TV comedy based on his illness.
The Back to the Future star will play a father of three dealing with the degenerative nervous system disorder.
NBC television called Fox "utterly relatable, optimistic, and in a class by himself".
In recent years, Fox gradually returned to TV with recurring roles in the likes of Boston Legal and The Good Wife.
However, the new 22-episode sitcom marks his first long-term commitment to a show since he left political comedy Spin City in 2000.
"I have no doubt that the character he will create - and the vivid family characters surrounding him - will be both instantly recognizable and hilarious," said NBC Entertainment Chairman Robert Greenblatt.
http://www.bbc.co.uk/news/entertainment-arts-19329468