Originally Posted by georgeyw

What about say

- you are editing a video and have the preview panel on the second monitor
- you are coding and have the test page / site / whatever on the second site
- you are writing a description of a gallery on one monitor and have the second monitor with the gallery open
- you are communicating on skype / icq / whatever about a problem you see on a website
- have a clip playing whilst writing a description about it

Lots of reasons to run multiple monitors - prefer it myself over the one for the reasons listed above and a heap more.