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An unconfirmed US media report says Lance Armstrong has confessed to talk show host Oprah Winfrey that he used performance-enhancing drugs during his cycling career.
Armstrong recorded the extensive interview this morning, just hours after apologising to staff at his Livestrong Cancer Foundation over his fall from grace.
It was Armstrong's first interview since being stripped of his seven Tour de France crowns.
Winfrey tweeted:
Just wrapped with @lancearmstrong More than 2 1/2 hours . He came READY!
News outlet Associated Press reported that a "source familiar with the situation" says Armstrong confessed to doping.
Winfrey's OWN network would not confirm or deny the report.
"We are not confirming any specific details regarding the interview at this time," a spokesman said.
The interview will go to air on Friday morning.
Winfrey confirmed she will appear on CBS television this evening to talk about it.
Armstrong has always denied using drugs and has remained silent since allegations were levelled against him by the US Anti-Doping Agency (USADA) in October.
"He's appeared on the shows many times and he's recognised that as the medium in which to tell all.
Cycling commentator Phil Liggett
Cycling commentator Phil Liggett believes the Winfrey interview will likely have yielded some kind of doping admission.
"He must have given this an awful lot of thought and he must have felt the net was finally closing in on him, and how was he going to come out reasonably well," Liggett said.
"I believe he knows Oprah.
"He's appeared on the shows many times and he's recognised that as the medium in which to tell all.
"That's what I feel is going to happen."
A Livestrong spokeswoman says Armstrong earlier held private talks with staff in which he pledged to help restore the foundation's reputation.
"Lance came to the Livestrong Foundation's headquarters today for a private conversation with our staff and offered a sincere and heartfelt apology for the stress they've endured because of him," Livestrong spokeswoman Rae Bazzarre said.
She added that Armstrong - a cancer survivor who founded the charity in 1997 - urged Livestrong staffers "to keep up their great work fighting for people affected by cancer."
Liggett says he is glad that Armstrong apologised.
"I'm rather pleased that Lance has finally come out and he's chosen, first of all, to go to his foundation because his heart was really in that foundation," Liggett said.
"Once the story broke back in October, he resigned as the chairman of Livestrong.
"But those people on the foundation have been so hard working for his cause and I'm glad he's chosen to go there first.