I switched fulltime to Mac last fall and thought about these same questions. I had always been a Outlook user, but wanted to change that. Sparrow looked really good with the best 3rd party reviews but all my mac friends said just use mail.app to start with and try it out even it it is a system application and I love it, works great.
(Plus it works sooooooo f'in perfectly with timemachine so if something really messes up, getting everything replaced right back is a breeze. Try doing that with Outlook)
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