Originally Posted by Tent Pitcher

From a technical standpoint, it does not matter, it certainly can be done with no problem.

From an SEO standpoint, make sure that you have some unique, quality content to balance out all of the ads and links if you are trying to build a web presence. Link farms are punished severely.

I guess the only question I would ask is why? Ads are ads, and assuming your Juicy Ads campaigns are configured similar to your PlugRush campaigns, you will not likely increase your clicks or conversions to one or the other by serving ads from both.