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Varnish "can" be very good, but with dynamic sites you'll need to dip a lot into its configs and exclusion files etc. to make sure which pages get cached and which don't. With e-commerce it can be a bitch, more so when you have a pair of them load balancing.
Look at something like new relic as well, that can monitor your apache/PHP/MySQL an tell you down to the lines of code what is and isn't performing. It may well identify a bottle neck elsewhere rather than just a lack of grunt to handle requests.
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