Originally Posted by CDSmith

That's correct. Like the instructions say, the final (hard) deadline for each week is on Sunday, but if you want to take advantage of the points the early game(s) bring each week (recommended!) then you need to get your picks in before the Thursday game.

NOTE: You can still alter the rest of your picks after the Thursday game if you wish. Sundays at 1 pm EST will always be the final deadline.

If you make your picks after Thursday but before Sunday's deadline you simply lose your top weighted pick is all. (a potential 32 points though, so it's a lot to lose)