I would recommend having a fully fledged mobile version of your website, if you dont have it, by now. The standard, these days, is to make 50% from the desktop version, and 50% from your mobile version of your site (as mobile is much more profitable).
The best way to achieve this, is to work with websites like
Bitter Strawberry, and
Sex Goes Mobile,and be very familiar with what they do. Mobile popunders from
Plugrush are an important part of equation too.
If we are talking about high traffic websites, you may want to start testing
First Mobile Cash, and
VPS Mobile, as these are somehow more advanced (they may turn out to be more profitable, on certain xxx sites).
But
Bitter Strawberry is a big number one.