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I have always suffered from it, I used to go from high to low. When I had cancer I contemplated suicide. The specialist put me on Cipralex and I'm fine. Nothing like I imagined, it doesn't numb me. Makes me feel fine.
As AK says, you need to see a doctor.
It would help if you identify what gets you down, like frustration, loneliness, lack of fulfillment, etc.
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