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One of our clients have +600TB images, with two Windows 2012R2 servers (on Hyper-V with 8Gig of Ram and 8vCPU). The Application frontend sees a SMB3 share that I can just add servers/LUN's to if needed. But so far it have a throughput of about 1,5mill IOPS.
The Storage is on a Tintri solution, but we are planning to set up a tiered storage for a nearline Archive/backup on the cheaper(slower) SAN.
It's really really simple to set up today, but it depends on what you want/need in regards to CDN or Clustering
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