Originally Posted by CyberSEO

O'rly? Here is the plugin which does everything you are asking for: Gallery Magic.

It generates galleries ("rest of small thumbnails in a row below or column on the side of big thumbnail"). To display it with a light box, you just need to install a freeware light box plugin") and adds them to your WP site as pages/posts. Also it makes featured images which are "1 big thumbnail".

The result will look like this: Playboy Centerfolds and Gorgeous Babes. Actually that site is powered by the CyberSEO plugin, but you can have exactly the same result with Gallery Magic too, except video embeds (Gallery Magic works with pictures only). With Gallery Magic you can import 1000's of galleries almost instantly from a usual FHG text dump, which is provided by 99.9% of existing affiliate programs. The plugin will generate posts/pages for every gallery, upload actual pictures to your host, crop thumbnails, generate features images, tags, insert custom ads etc.