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I don't tweet porn, but I do have a lot of success promoting my music with it. I write bots (not API, the keys get deleted). For my users database, I did a few things. I scrape people who follow similar artists, and more importantly people who engage with similar artists. I filter out people who haven't tweeted in over a week to get a higher ratio of active users. For each account I have (about 10) I can send 1,000 tweets mentioning 3 people each/day. I also have a separate DB of about 5,000 people who have liked or retweeted my own tweets. When I make a new track those are the people I hit first.
You could probably follow that model with adult stuff as long as you mine your users from the right sources and filter them appropriately.
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