I had that done as a custom mod by Nick from RoboScripts on his PHP script, for custom posts on the site.
But also had that done by another dev on a WP project.
It renames the image according the post title/permalink.
So when the link is /sexy-hot-girl it renames the image to sexy-hot-girl.jpg
Sure that is possible and a great mod!
But I´m not too technical so I cannot tell you exactly how
Also you maybe want to get an alt tag added automatically?
And the title + alt tag on the thumbs in the thumb overview??
Another great idea