As mentionned, looks like it's a DB issue.
This is often due to poorly designed template code (too many queries). You'll also need to integrate a better caching system. Users hitting your site should rarely require SQL queries if your site is properly cached.
If it's not a caching issue, then there is something in your site that is running queries and overloading your system. This is usually caused by a plugin trying to audit your site or something.
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