Working the web is just a numbers game so I would say first thing you need to do no matter what product or service you are planning on selling is FOCUS ON GETTING TRAFFIC!
No matter what the sources of your traffic are be sure that you can control where it all goes either by sending it all to one site (a hub) or by redirecting it via your server or scripts since this will allows be your most valuable assett. It doesn't matter how kick ass your site looks or how great your product is if nobody is seeing it then nobody is buying it.
With enough traffic you can literally sell ice to eskimoes!
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