AdultWebWare is still my personal choice. The script handles more than I ever could desire and new features are constantly being added. It takes very little resources and is lightning fast. Support is always available and right there to handle your needs without delay. It is fantastically priced specially for what it offers. I never have any errors with it that are script based (I find out its a mysql reboot issue or something when it rarely happens).
Then to top it off they offer a 111% money back guarantee, yes that's right they will not only refund your money but pay some extra for the time.
We use it on all of our sites, and I have watched as other CMS programs have came and gone only attempting to offer what this does.