Maple syrup urine disease - GoFuckYourself.com

Rochard · 10-05-2006, 09:38 PM

I try to read about current events related topics, and last night I was reading about the Amish when I came across Maple syrup urine disease. No kidding.

Maple syrup urine disease (MSUD) is an autosomal recessive metabolic disorder due to a deficiency of Branched chain α-keto acid dehydrogenase (BCKDH) that leads to elevated concentrations of leucine, isoleucine, and valine (branched amino acids) in the blood and urine. Characterized by the urine having an odor similar to that of maple syrup, this results in severe mental retardation, and seizures. Because of a genetic bottleneck effect, MSUD has a much higher prevalence in children of Amish and Mennonite descent. Also called branched chain ketoaciduria.

From early infancy, the condition is characterized by poor feeding, vomiting, lack of energy (lethargy), seizures, and mental retardation. The urine of affected infants has a distinctive sweet odor, much like burned caramel, that gives the condition its name. Maple syrup urine disease can be life-threatening if left untreated.

Maple syrup urine disease can be classified by its pattern of signs and symptoms or by its genetic cause. The most common and most severe form of the disease is the classic type, which appears soon after birth. Variant forms of the disorder appear later in infancy or childhood and are typically less severe, but still involve mental and physical retardation if not treated.

Violetta · 10-05-2006, 09:42 PM

wtf? sucks to have that! No example of someone having it? Mel Gibson? Paris Hilton?

ER!C L!VE · 10-05-2006, 09:51 PM

Dude, I thought you were just fucking around. I would just think I fucked a dirty ass bitch if my piss was maple syrup in consistancy..

http://en.wikipedia.org/wiki/Maple_syrup_urine_disease

Spunky · 10-05-2006, 09:53 PM

I never liked syrup at all.Clogs you up like oil

rodney25 · 10-05-2006, 10:15 PM

Thank goodness, I never had that thing here.

BIGTYMER · 10-05-2006, 10:27 PM

Whoa!! Sick sheittt.

10-05-2006, 09:38 PM	#1
Rochard Jägermeister Test Pilot Industry Role: Join Date: Dec 2001 Location: NORCAL Posts: 73,461	Maple syrup urine disease I try to read about current events related topics, and last night I was reading about the Amish when I came across Maple syrup urine disease. No kidding. Maple syrup urine disease (MSUD) is an autosomal recessive metabolic disorder due to a deficiency of Branched chain α-keto acid dehydrogenase (BCKDH) that leads to elevated concentrations of leucine, isoleucine, and valine (branched amino acids) in the blood and urine. Characterized by the urine having an odor similar to that of maple syrup, this results in severe mental retardation, and seizures. Because of a genetic bottleneck effect, MSUD has a much higher prevalence in children of Amish and Mennonite descent. Also called branched chain ketoaciduria. From early infancy, the condition is characterized by poor feeding, vomiting, lack of energy (lethargy), seizures, and mental retardation. The urine of affected infants has a distinctive sweet odor, much like burned caramel, that gives the condition its name. Maple syrup urine disease can be life-threatening if left untreated. Maple syrup urine disease can be classified by its pattern of signs and symptoms or by its genetic cause. The most common and most severe form of the disease is the classic type, which appears soon after birth. Variant forms of the disorder appear later in infancy or childhood and are typically less severe, but still involve mental and physical retardation if not treated. __________________ “The choice is no longer between right or left. The choice is between normal and crazy.” - Sarah Huckabee Sanders YNOT MAIL \| THE BEST ADULT MAILING SOLUTION

10-05-2006, 09:42 PM	#2
Violetta Affiliate Join Date: Jul 2004 Posts: 28,735	wtf? sucks to have that! No example of someone having it? Mel Gibson? Paris Hilton? __________________ M&A Queen

10-05-2006, 09:51 PM	#3
ER!C L!VE Confirmed User Join Date: Feb 2005 Location: WORLDW!DE Posts: 724	Dude, I thought you were just fucking around. I would just think I fucked a dirty ass bitch if my piss was maple syrup in consistancy.. http://en.wikipedia.org/wiki/Maple_syrup_urine_disease __________________ www.BackroomCastingCouch.com www.ExploitedCollegeGirls.com www.FCUKCash.com

10-05-2006, 09:53 PM	#4
Spunky I need a beer Industry Role: Join Date: Jun 2002 Location: ♠ Toiletville ♠ Posts: 133,934	I never liked syrup at all.Clogs you up like oil __________________ *YOUR INFORMATION HERE*

10-05-2006, 10:15 PM	#5
rodney25 Confirmed User Join Date: Jun 2005 Posts: 7,090	Thank goodness, I never had that thing here. __________________ AFFORDABLE Hosting -- Extreme Dependability -- FULL Service ICQ ME for DAMN GOOD HOSTING DEALS: 5380773

10-05-2006, 10:27 PM	#6
BIGTYMER Junior Achiever Industry Role: Join Date: Nov 2004 Location: Walled Garden Posts: 17,066	Whoa!! Sick sheittt.