MRI contrast agents leave heavy metal deposits in brain
 

WASHINGTON, June 25 (UPI) -- Repeated use of specific "linear"-type gadolinium-based contrast agents, or GBCAs, for MRIs leads to deposits of the heavy metal gadolinium in the brain, according to a new study.

The agents have been widely used in MRIs since their approval in 1988, with roughly 30 million doses given each year.

"This important safety issue may lead to certain linear GBCAs not being used in the future," said Val M. Runge, M.D., of University Hospital Zurich, in a press release. Runge, editor-in-chief of the journal Investigative Radiology, which published the study, first proposed the concept of using gadolinium as a contrast agent in 1982 and demonstrated the effectiveness of the first GBCA developed in 1984. "All of the currently approved GBCAs should be evaluated by the methods used" in this study, he added.

Based on recent studies that have called into question the safety of GBCAs, researchers compared the MRI results of three groups of rats. One group was given high doses of traditional linear GBCAs, the second group was given a different GBCA, the "macrocyclic" agent called gadoterate meglumine, and the third group received saline.

The study, funded by Guerbet, the manufacturer of gadoterate meglumine, found that rats given linear GBCAs showed abnormalities in their cerebellums on MRIs that researchers determined to be deposits of gadolinium.

Study: MRI contrast agents leave heavy metals in brain - UPI.com

built-in tin foil hat

I see you've been treated a shitload of contrast then.

Mri
 

Hadn't noticed being any crazier than I already am after I had a brain scan.

But sure left the doctor and nurse laughing. Hate needles, so my girlfriend went with me. She saw the look of fear on my face, just before the IV. In front of the doctor & nurse, said if I didn't calm down, she was going to pull up her top and stick a tit in my mouth.

Sure they never heard that one before. And she would have done it.

Don't have a MRI then.

Paper or plastic?

clicked on the thread going like "oh goody a music thread again" :Oh crap

There is nothing sexier than a lady who is a freak in the sheets and a lady in the streets.

Better luck next time.

:thumbsup :thumbsup