Vampire bat saliva improves stroke outcome? - GoFuckYourself.com

digifan · 02-05-2005, 09:53 PM

Lol that's funny... I have no idea how the scientists experiment with stuff like that? Anyway here's the info :D

Bat Saliva Drug May Improve Stroke Outcome

NEW ORLEANS (Reuters Health) - The results of a small study suggest that desmoteplase, an investigational clot-busting drug derived from vampire bat saliva, safely restores blood supply to the brain when administered up to 9 hours after a stroke occurs.

Dr. Anthony Furlan of the Cleveland Clinic Foundation in Ohio said that the rate of blood flow restoration in stroke patients who were randomly assigned to intravenous treatment with desmoteplase was 53.3 percent, compared with 37.5 percent in patients randomly assigned to receive placebo.

Furlan presented results of the Dose Escalation study of Desmoteplase in Acute Ischemic Stroke (DEDAS) at a late-breaking clinical trials session on Friday at the American Stroke Association International Stroke Conference 2005.

A lower dose of desmoteplase was not superior to placebo. However this dose was effective in an earlier European study and Furlan said it will be investigated in a large, multinational study of desmoteplase that will begin enrollment in April.

In terms of safety, there were no symptomatic episodes of bleeding in the brain, a potential side effect of this type of therapy. An earlier study of desmoteplase reported one symptomatic bleeding episode.

"Combining both studies the hemorrhage rate was 2 percent, which is less than the 6 percent hemorrhage rate reported with tissue plasminogen activator," he said. Tissue plasminogen activator, or tPA, is another clot-dissolving drug, which is currently on the market.

Furlan presented the results for 37 patients who were treated within 3 to 9 hours after they had a stroke. All of the patients had a National Institutes of Health (news - web sites) Stroke Score (NIHSS) between 4 and 20.

Eight patients were randomly assigned to receive placebo, 14 to low-dose desmoteplase and 15 to a higher dose of desmoteplase.

After 90 days, 9 patients in the high-dose arm had clinical improvement (60 percent) versus 2 in the placebo arm (25 percent) and 4 in the lower dose arm (28.6 percent)

The study was funded by Paion Pharmaceutical in Aachen, Germany. The phase III trial will be supported by Forest Pharmaceuticals of St. Louis.

http://story.news.yahoo.com/news?tmp...e_batsaliva_dc

Evil1 · 02-05-2005, 10:11 PM

I'm going to go out tommorow and get a pet bat just incase I ever need bat juice.. thanks.

digifan · 02-05-2005, 10:13 PM

Quote:

Originally Posted by Evil1

I'm going to go out tommorow and get a pet bat just incase I ever need bat juice.. thanks.

digifan · 02-05-2005, 10:16 PM

It's silly I agree with you on that.. but they are spending a lot of money on research like that and it made me wonder where these ideas come from... maybe remembering their grand-grandmothers' secret tips or what?

Pipeline Q · 02-05-2005, 10:18 PM

I had one of these in the house last summer.

digifan · 02-05-2005, 10:22 PM

That's what I call prevention

uno · 02-05-2005, 10:45 PM

Quote:

Originally Posted by digifan

It's silly I agree with you on that.. but they are spending a lot of money on research like that and it made me wonder where these ideas come from... maybe remembering their grand-grandmothers' secret tips or what?

They spend money on it because it makes sense and could potentially help. They knew what the chemical did, they know what strokes do, and put 2 & 2 together.

02-05-2005, 09:53 PM	#1
digifan The Profiler Industry Role: Join Date: Oct 2002 Location: ICQ 76281726 and I'm female Posts: 14,618	Vampire bat saliva improves stroke outcome? Lol that's funny... I have no idea how the scientists experiment with stuff like that? Anyway here's the info :D Bat Saliva Drug May Improve Stroke Outcome NEW ORLEANS (Reuters Health) - The results of a small study suggest that desmoteplase, an investigational clot-busting drug derived from vampire bat saliva, safely restores blood supply to the brain when administered up to 9 hours after a stroke occurs. Dr. Anthony Furlan of the Cleveland Clinic Foundation in Ohio said that the rate of blood flow restoration in stroke patients who were randomly assigned to intravenous treatment with desmoteplase was 53.3 percent, compared with 37.5 percent in patients randomly assigned to receive placebo. Furlan presented results of the Dose Escalation study of Desmoteplase in Acute Ischemic Stroke (DEDAS) at a late-breaking clinical trials session on Friday at the American Stroke Association International Stroke Conference 2005. A lower dose of desmoteplase was not superior to placebo. However this dose was effective in an earlier European study and Furlan said it will be investigated in a large, multinational study of desmoteplase that will begin enrollment in April. In terms of safety, there were no symptomatic episodes of bleeding in the brain, a potential side effect of this type of therapy. An earlier study of desmoteplase reported one symptomatic bleeding episode. "Combining both studies the hemorrhage rate was 2 percent, which is less than the 6 percent hemorrhage rate reported with tissue plasminogen activator," he said. Tissue plasminogen activator, or tPA, is another clot-dissolving drug, which is currently on the market. Furlan presented the results for 37 patients who were treated within 3 to 9 hours after they had a stroke. All of the patients had a National Institutes of Health (news - web sites) Stroke Score (NIHSS) between 4 and 20. Eight patients were randomly assigned to receive placebo, 14 to low-dose desmoteplase and 15 to a higher dose of desmoteplase. After 90 days, 9 patients in the high-dose arm had clinical improvement (60 percent) versus 2 in the placebo arm (25 percent) and 4 in the lower dose arm (28.6 percent) The study was funded by Paion Pharmaceutical in Aachen, Germany. The phase III trial will be supported by Forest Pharmaceuticals of St. Louis. http://story.news.yahoo.com/news?tmp...e_batsaliva_dc __________________ [email protected] Webair Rocks

02-05-2005, 10:11 PM	#2
Evil1 Confirmed User Industry Role: Join Date: Mar 2002 Posts: 3,893	I'm going to go out tommorow and get a pet bat just incase I ever need bat juice.. thanks. __________________

02-05-2005, 10:16 PM	#4
digifan The Profiler Industry Role: Join Date: Oct 2002 Location: ICQ 76281726 and I'm female Posts: 14,618	It's silly I agree with you on that.. but they are spending a lot of money on research like that and it made me wonder where these ideas come from... maybe remembering their grand-grandmothers' secret tips or what? __________________ [email protected] Webair Rocks

02-05-2005, 10:22 PM	#6
digifan The Profiler Industry Role: Join Date: Oct 2002 Location: ICQ 76281726 and I'm female Posts: 14,618	That's what I call prevention __________________ [email protected] Webair Rocks

02-05-2005, 10:18 PM	#5
Pipeline Q Confirmed User Join Date: Dec 2004 Posts: 3,891	I had one of these in the house last summer.